

Dr. Pimple Popper: Breaking Out
Dr. Sandra Lee, also known as Dr. Pimple Popper, is the most famous dermatological surgeon in the world and an internationally beloved personality. She has dedicated her life to sharing her incredible skills with her huge audience, as she helps hundreds of suffering patients who are unable or unwilling to find treatment for their painful, oozing cysts, fatty tumors, and infinitely complex, life-affecting dermatological issues. Now, Dr. Lee is ready to take her practice to the next level. The doctor has made modern additions to her main office which include an entire new wing of patient rooms, and many new staff and doctors. For the first time, Dr. Lee will also be providing intimate self-shot footage of her life outside the office.
Cast

Sandra Lee
Self
Seasons

E1Lessons in Pimple Popping
Apr 21, 2025
"Dottie the Body" lost her confidence when a large bump started growing between her thighs; Dr. Lee brings in a new, young doctor to help Tim with his big, bumpy nose; Karime is insecure about her birthmark that looks like a black eye.

E2A Juicy Secret
Apr 28, 2025
Katrina has oozing, smelly boils that have taken over her life. Kim's head-to-toe tumors interfere with her sleep apnea mask, resulting in constant exhaustion. Dr. Lee and a medical student trainee help Emil and his wife, who are afraid the bump and lesion on his back might be cancerous.

E3Superglue to the Rescue
May 5, 2025
Tierra is a musician with massive bumps on her ears that hold her back from performing. Dr. Zoe assists Dr. Lee helping Ryan, whose numerous head bumps undermine his life journey. Ann keeps a great attitude even as she lives with everyday pain caused by her genetic skin condition.

E4Call Me Big Popper
May 12, 2025
Dr. Lyndsey assists Dr. Lee with Lance's notoriously big bump that halted his rap dreams. Shelby has lost control of her sweet tooth, her health, and the mystery bumps she has developed. Dr. Lee proposes a long-shot cure for Jante, who has been losing pigment in her skin as well as her confidence.

E5Senior Cyst-izen
May 19, 2025
Anthony is trying to move on from his troubled past, but his huge thigh lump is holding him back. Mary has a mysterious 70-year-old bump that amazes Drs. Lee and Tomassian. Sultana has a shocking red rash on her face that affects her social media success.

E6Jaw Dropper
May 26, 2025
Dr. Lyndsey joins Dr. Lee to help David, who is fearful that the lump on his jaw might be cancer. Carla has a large, mysterious bulge on her thigh that concerns Dr. Lee. James has over 70 skin tags that he wants removed so he can get his beach body back.

E7Holey Moley
Jun 2, 2025
Bill's swinging arm growth prevents him from living his retirement dreams. Regina distracts from the many moles on her face with a vibrant style. Budding med student Gili helps Dr. Lee solve the mystery of Cowboy Carter's extensive rash.

E8Tag Team My Bumps
Jun 9, 2025
Dr. Lee asks Dr. Zoe to help double-team needle-shy Mary Ann's crusty skin. Isaiah's mom is concerned he is ignoring the large, growing lump over his lower spine. Maressa worries about the dangers of treating the oozing skin covering her ankles and body.

E9Triangle of Death
Jun 16, 2025
Jason has become a recluse because of a giant growth on the back of his neck.

E10Nurse Bumpy Head
Jun 23, 2025
Bryan has a genetic condition that may be causing the huge mystery bumps on his head.

E11Psoria-Sisters
Jun 30, 2025
Dave is a firefighter and avid cyclist whose bump gets in the way of wearing various helmets. Bree empowers others on social media by accepting her own psoriasis, but it has recently become too painful to endure.

E12Buffalo Hump Bump
Jul 7, 2025
Dee has the voice of an angel, but her huge neck hump has stolen her passion to sing. Young Eli wants to be a chef, but feels ashamed of his cheek bump and worries removing it could paralyze his face.

E13My Head Laid An Egg
Jul 14, 2025
Stephanie has dreams of being a caterer, but is humiliated by her giant baseball-sized scalp bump. Deb is afraid that the growth on the side of her knee may eventually paralyze her.

E14Needle Little Help
Jul 21, 2025
Jimmy is a Charleston firefighter whose myriad of torso bumps make it painful to play with his young son.

E15Bye Bye Booty Bump
Jul 28, 2025
Denise has a growth on her booty, but scarring from a previous trauma has kept her from getting it removed. Zachary is a drag artist whose touring career is dragged down by his painful, debilitating psoriasis.

E16Hex Marks the Spot
Aug 4, 2025
Rachael is a caretaker whose arm bump interferes with helping her disabled bestie. Medical student Gili assists Dr. Lee with Christian's painful back bump as his stuffed animal companion watches.

E17Third Eye Blinded
Aug 4, 2025
Allie is a free spirit whose polyamorous lifestyle is ruined by the gumball-sized bump above her eye. Film buff Andrew's psoriasis and multiple body bumps have held him back from starting a family with his wife, Gift.

E18Beach Bump
Aug 11, 2025
Jon's huge, 25-year-old shoulder blade bump is ruining his family beach days and risking his health. April wants the wedding of her dreams but feels hideous in gowns due to her bumpy underarm "threast."

E19My Unlovely Lady Lumps
Aug 18, 2025
Tobi is having trouble re-entering the dating pool because of symmetrical, tush-shaped bumps around her spine. Tia is a beautiful young woman whose huge, shiny scalp growth has sent her into self-imposed exile.

E20Lump In My Throat
Aug 25, 2025
Jack searches for the confidence to try surgery on his throat bump, after fainting during a previous attempt. Kristan is a young, bubbly gym teacher who has given up on love after discovering a growth on her back.
In season 2, Dr. Lee and her team tackle never-before-seen cases that push the limits of dermatology, delivering life-changing transformations and emotional journeys that go far beyond the surface. As she molds the next generation of poppers, Dr. Lee continues her mission to restore confidence and improve lives - one pop at a time. But this season, Dr. Lee encounters an unexpected challenge that could change everything.

E1A Mother’s Lump
Apr 20, 2026
Angela has a huge, melon-sized growth on the back of her neck that she fears will ruin her daughter’s wedding–and her daycare business.

E2Gone in Cyst-y Seconds
Apr 27, 2026
John is trying to get over his bumpy past.

E3A Cheeky Bump
May 4, 2026
Car lover Dave has 17 huge, painful head bumps that concern his girlfriend.

E4The Danger Triangle
May 11, 2026
Jeana has huge, spherical growths dangling from her ears.

E5A Bronx Bump
May 18, 2026
Tana deals with a forehead bump that has destroyed her business aspirations.

E6It's All in the Hips
May 25, 2026
John is bound to a wheelchair after his legs have become too swollen.
E7Backcountry Bump
Jun 1, 2026
Veronica has a huge mango-sized growth on her back. Thomas has a deep passion for cosplay but is too embarrassed to dress up due to the large bump on their head. Dr. Lyndsey returns to help Dr. Lee shape former golf pro Ken's lumpy, bumpy nose.
E8A Pain In The Bump
Jun 8, 2026
Candace is a singer and doula whose huge face bump is stealing her youth. Christian has ignored the terrifying growth hanging off his tush. Otito worries that the extreme, thickened skin on her hands and feet will end her dental career.

E9Life Lesions
Jun 15, 2026
Dr. Tolson learns how to help Dr. Lee treat Mary Beth's bumpy, mysteriously-changing face lesions. Dr. Ortiz steps in to help Kathy, who has thousands of red dots on her body that keep her from confidently wearing a bathing suit.

E10Retraining The Brain
Jun 22, 2026
Dr. Lee, occupational therapist, arrives to help re-train her body post-stroke. Justin arrives with a body-covering, angry rash. Dr. Lee can only observe as Dr. Farhang attempts to remove AJ's huge forehead bump.

E11Two Derms Are Better Than One
Jun 29, 2026
As Dr. Lee continues to recover from her stroke, she calls in reinforcements from Montana — her old dermatology residency pal, Dr. Kristen Townley. She assists Dr. Lee to help Cashanna, who is so ashamed of the clusters of bumps covering her eyelids.
E12Painless Lee and Fearless Townley
Jul 6, 2026
As she continues to recover from her stroke, Dr. Lee again enlists her Montana friend Dr. Kristen Townley to remove Paul’s concerning windpipe bump. The doctors also try to help Kellie, who has a large, possibly vascular lump on the side of her head.
Videos
Storyline
Dr. Sandra Lee, also known as Dr. Pimple Popper, is the most famous dermatological surgeon in the world and an internationally beloved personality. She has dedicated her life to sharing her incredible skills with her huge audience, as she helps hundreds of suffering patients who are unable or unwilling to find treatment for their painful, oozing cysts, fatty tumors, and infinitely complex, life-affecting dermatological issues. Now, Dr. Lee is ready to take her practice to the next level. The doctor has made modern additions to her main office which include an entire new wing of patient rooms, and many new staff and doctors. For the first time, Dr. Lee will also be providing intimate self-shot footage of her life outside the office.
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