Storyline
Pinky and Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is self-centered and scheming; Pinky is good-natured but feebleminded. In each episode, Brain devises a new plan to take over the world, which ultimately ends in failure, usually due to Pinky's idiocy, the impossibility of Brain's plan, Brain's own arrogance, or just circumstances beyond their control.
Episodes
Specials
No overview available for this season.
The Start of All Things Wacky
Jun 29, 2026
A featurette with Senior Producer Tom Ruegger, Writer Peter Hastings, the voices of Pinky and the Brain stars, Rob Paulsen and Maurice LaMarche, and voice director Andrea Romano as they discuss antidotes and antics about Steven Spielberg and why they had so much fun at work.
Win Big
Jun 29, 2026
Pinky and the Brain Short Brain competes on a trivia game show entitled ""Gyp-Parody"" to win money to buy a device to take over the world.
Where Rodents Dare
Jun 29, 2026
Pinky and the Brain Double Length Short With one of his new inventions, Brain plans to freeze all the leaders of the world when they are at an international peace conference in the Alps. Pinky and the Brain have a hard time getting to the peace conference, but when they finally do Brain's plans are foiled when someone traps them while they stand on a plate of cheese. The two mice only succeed in freezing themselves.
Battle for the Planet
Jun 29, 2026
Pinky and the Brain Short Brain wants to take over the world by tricking people into thinking that an aliens are invading. Brain arranges a pirate broadcast with himself as a reporter and Pinky as an alien. Brain says that aliens have landed and that people should flee from the cities. Pinky, however, has trouble with his costume. They complete their fake broadcast and wait for people to flee the cities. The next day, however, they look at the newspaper and see that everyone thought that the broadcast was a hilarious fake.
Pavlov's Mice
Jun 29, 2026
Pinky and the Brain Short In turn of the century Russia, Pinky and the Brain are conditioned to respond in strange ways to the sound of bells. Brain plans to take over the world by stealing the crown jewels of Russia. Unfortunately, his conditioning prevents him from successfully getting the jewels.
Opportunity Knox
Jun 29, 2026
Pinky and the Brain Short Brain wants to steal all of the gold out of Fort Knox. He develops a chemical that causes sneezing fits in people. Pinky and the Brain get to Fort Knox and use the chemical on the guards. They break into the safe and realize that they can't steal the gold because the gold bars are too heavy for the mice to lift.
Are You Pondering What I'm Pondering?
Jun 29, 2026
Featurette with the voices of Pinky & the Brain stars Rob Paulsen and Maurice LaMarche, and voice director Andrea Romano as they discuss anecdotes and antics about Steven Spielberg, Tom Ruegger and why they all had so much fun at work!
It's All About The Fans
Jun 29, 2026
The Audition
Jun 29, 2026
Mark Hamill (Star Wars) and Wayne Knight (Seinfeld) answer a casting call to do the voices of Pinky and The Brain for a future movie - and get a surprise coaching session from original Pinky and The Brain voices Rob Paulsen and Maurice LaMarche.
Season 1
No overview available for this season.
Das Mouse
Sep 09, 1995
Brain hatches a plot to hypnotize people, but he needs white crab meat to succeed. In order to get the crab meat, he takes a submarine to the wreck of the Titanic. Unfortunately, the CIA spots his sub and orders its destruction.
Of Mouse and Man
Sep 17, 1995
Brain plans to take over the world by creating a voice mail system that will tie up everyone on the planet long enough for him to take over. In order to do this he needs money. He decides to get it by getting a job and then staging an accident in order to sue the company.
Tokyo Grows
Sep 24, 1995
Brain uses an enlarging ray to make himself and Pinky four hundred feet tall. With Pinky dressed as a Gollyzilla, Brain stages a fight to make himself look like hero. But then the real Gollyzilla shows up.
That Smarts
Sep 24, 1995
Brain makes Pinky smarter so his stupidity won't ruin anymore plans.
Brainstem
Sep 24, 1995
Pinky and Brain perform a song about the brain.
Pinky & The Fog
Oct 01, 1995
Brain gains the ability to cloud the minds of men with his voice. He tries to get on the radio by adapting the persona of "The Fog". Unfortunately his plan falls apart when he gets to the studio.
Where No Mouse Has Gone Before
Oct 08, 1995
Brain hears that a space probe is about to be launched. On the probe is a plaque with a representation of man and woman. Brain changes the plaque to make it appear that he rules the world. Aliens discover the probe and take Pinky and the Brain to their planet where they honor them just like they are "honored" on Earth.
Cheese Roll Call
Oct 08, 1995
Pinky sings about cheese.
Brainania
Nov 12, 1995
The Brain hatches a plan to take over the world by using static electricity to shock the world into submission. Unfortunately he needs several billion dollars to build a giant clothes dryer. Pinky and the Brain head to Island X where they set up a fake country and hope to get a giant foreign aid loan from the United States.
TV or Not TV
Nov 19, 1995
Brain develops a special pair of dentures that can produce a smile that can hypnotize anyone who is not wearing a special pair of sunglasses. In order to take over the world, he needs people to see the mesmerizing smile. He figures that he needs to get on TV and in order to do that he has to become a celebrity.
Napoleon Brainaparte
Nov 26, 1995
While France awaits Napoleon's triumphant return from Austria, Brain develops a recipe for exploding crepe-suzettes in an effort to conquer France. He uses the recipe in a cooking class and when the crepes explode, he is arrested. When he is taken to prison, however, his luck begins to change when people mistake him for Napoleon Bonaparte.
A Pinky and the Brain Christmas
Dec 13, 1995
Pinky and the Brain head to the North Pole. Pinky just wants to see Santa, but the Brain has a more sinister plan. He wants pretend to be an elf so that he can mass produce a hypnotic doll named "Noddle Noggin" in Santa's workshop. He then hopes that Santa will distribute the toy all over world so he can take over.
Snowball
Jan 21, 1996
Brain comes face to face with his former friend and now enemy, Snowball. And it seems Snowball has his own plans to take over the world.
Around the World in 80 Narfs
Feb 04, 1996
In Victorian England, the Brain realizes that he can take over the world by becoming president of the "Pompous Explorers Club". since the position usually leads to the Prime Ministership of England. In order to become president of the club, he must make it around the world in seventy-nine days.
Fly
Feb 11, 1996
Brain plans to melt the ice caps with the Hubble Space Telescope once he buys everything higher than the 39th floor.
Ambulatory Abe
Feb 25, 1996
Brain hopes to take over the world by convincing everyone that Abraham Lincoln has been reincarnated. He takes up ventriloquism and plans on using a statue.
Mouse of La Mancha
Feb 25, 1996
Brain tells a group of mice the story of "Don Cerebro" a mouse driven by his dream to take over the world.
The Third Mouse
May 12, 1996
Pinky searches for the Brain in post-World War II Vienna. He misunderstands people when they try to tell him the Brain is dead and his misunderstandings lead to a series of misadventures.
The Visit
May 12, 1996
The Brain captures two mice for an experiment to aid in a plan for world domination. He discovers however that the two mice are his parents.
Season 2
No overview available for this season.
It's Only a Paper World
Sep 07, 1996
Brain tries to get all the people off Earth onto his paper mache creation, Chia Earth.
Collect 'em All
Sep 14, 1996
Using Johannes Gutenberg printing press, the Brain make a series of collectible trading cards.
Pinkasso
Sep 14, 1996
A successful modern artist is born and it's Pinky, trying to help fund Brain's new plan.
Plan Brain From Outer Space
Sep 28, 1996
Brain hopes his inter-galactic pen pal, Zalgar, will help him take over the world. But it turns out Zalgar likes to snack on brains.
The Pink Candidate
Nov 02, 1996
Pinky writes a letter to the newspaper criticizing the comic strip "The Family Circus". His letter, however, is misunderstood as a political statement that thrusts him to a spotlight that leads him to the Presidency of the United States. Pinky's administration, however, must deal with a scandal when the Brain's plans to take over the world are made public.
Brain's Song
Nov 09, 1996
Brain makes a tearjerker movie to make the world sad enough to make him leader.
Welcome to the Jungle
Nov 16, 1996
Animal rights activist think Pinky and the Brain are monkeys and release them into the jungle after taking them out of Acme Labs. The pair try to make it back home, but run into the Brain's old enemy Snowball.
A Little Off the Top
Nov 23, 1996
Brain tries to discover what makes the legendary Samson so strong.
Megalomaniacs Anonymous
Nov 23, 1996
When Brain comes to the conclusion he no longer wants to take over the world, he decides to help others who had his problem and the first one to be helped is Pinky.
The Mummy
Dec 28, 1996
Pinky and Brain get sealed in an Egyptian pyramid where a mummy is lurking about.
Robin Brain
Dec 28, 1996
Brain gets a group of men to steal money from the rich (ala Robin Hood) to pay for his new plot.
Two Mice and a Baby
Feb 01, 1997
Pinky and Brain stumble upon a super powered baby, who happened to arrive from an exploding alien world.
The Maze
Feb 01, 1997
Pinky and Brain have to brave a virtual reality maze to find a microchip crucial to Brain's new plot.
Brain of the Future
Feb 08, 1997
The mice's future selves arrive in the lab, sending them on a roller coaster ride through time to find a world domination kit.
Brinky
Feb 22, 1997
Pinky and Brain's DNA get merged during a cloning experiment, creating a new mouse.
Hoop Schemes
May 17, 1997
Pinky and Brain put together a basketball team as part of their next plan, but the fame may be swelling Brain's head.
Season 3
No overview available for this season.
Leave It to Beavers
Sep 08, 1997
Brain enlists the aid of beavers to gain control over the flow of rivers.
Cinebrania
Sep 08, 1997
The mice make a series of comedy films and hit the big time.
Pinky & The Brain ...and Larry
Sep 13, 1997
Pinky and Brain have a new companion, Larry, but their newest plan just doesn't seem to pan out.
Where the Deer and The Mousealopes Play
Sep 13, 1997
In their latest plan, Pinky and Brain try to take over the steel mills in Pittsburgh, Pennsylvania by pretending to be a part of an endangered species called the Mousealopes.
Brain Noir
Sep 13, 1997
It's 1946 and Brain's new plan gets interrupted when he and Pinky encounter Billie and Snowball.
Brain's Bogie
Sep 15, 1997
Brain gets caught up in winning a golf tournament, even though it interferes with his new plan.
Say What, Earth
Sep 15, 1997
After the Earth gets the power of speech from his Silitronlinguifactor device, Brain comes up with a new plan.
My Feldmans, My Friends
Sep 16, 1997
Brain tries to get a package meant for him back from his neighbor.
All You Need Is Narf
Sep 17, 1997
Pinky becomes a guru during the 1960s.
Pinky's Plan
Sep 17, 1997
It's Brain's birthday and Pinky plans a surprise party.
This Old Mouse
Sep 18, 1997
After getting a glimpse of his future, Brain abandons his attempts to take over the world and gets a job as a ski instructor.
Brain Storm
Sep 19, 1997
The mice are looking to control tornados, but a pest keeps getting in their way.
A Meticulous Analysis Of History
Sep 20, 1997
Brain sings about past and present world leaders' failures.
Funny, You Don't Look Rhennish
Sep 20, 1997
The mice need to get into a mine, but have to pretend to join a Amish-type society.
The Pinky Protocol
Sep 22, 1997
Brain's latest plan is a conspiracy theory about why he is not ruling the world.
Mice Don't Dance
Sep 26, 1997
Brain becomes a tap dancer with steam-powered legs in order to spread a subliminal morse code at the World's Fair.
Brain Drained
Sep 26, 1997
Brain is out of ideas for taking over the world, so he tries to get some from writers.
Brain Acres
Sep 27, 1997
Farmer Brain tries to grow an army of monster vegetables.
Pinky And The Brainmaker
Sep 29, 1997
Brain creates a cloning machine and plans to clone himself in order to create the best Celtic dance troupe the world has ever seen.
Calvin Brain
Sep 29, 1997
Brain masquerades as a fashion designer.
Pinky Suavo
Oct 04, 1997
Brain plans to use the Personalitron to give him irresistible charisma, but it winds up going to Pinky.
T.H.E.Y.
Oct 04, 1997
The mice learn of a secret organization, T.H.E.Y. (comprised of world leaders), and try to get in.
The Real Life
Oct 10, 1997
A house needed for Brain's latest plot becomes the set of a reality series about the people living there. So the mice become participants to get in.
Brain's Way
Oct 11, 1997
To save his Las Vegas casino, Brain works as a lounge singer.
A Pinky And The Brain Halloween
Oct 19, 1997
Mr. Itch offers Brain control of the world in exchange for his soul, but Brain refuses. In a shocking twist, Pinky sells his soul to make it happen and Brain soon decides to get his friend back.
Brainy Jack
Nov 02, 1997
Brain assumes the identity of Briany Jack, a hippie leader, and tries to create a peace chain to send a subliminal message.
Leggo My Ego
Nov 07, 1997
Brain's attempt to control Emperor Franz Josef get side tracked when he talks about his problems with psychiatrist Dr. Sigmund Freud.
Big In Japan
Nov 07, 1997
Brain enters the world of a sumo wrestling to acquire a paralyzing fish.
But That's Not All, Folks!
Nov 08, 1997
Brain takes control of a satellite to air his infomercial around the world, but the satellite belongs to the military and they want to capture whoever hacked into their systems.
Operation Sea Lion
Nov 14, 1997
Brain takes control over aquatic mammals for his latest plan and Pinky falls for a female sea lion.
You Said a Mouseful
Nov 14, 1997
Brain tries to change the Earth's weather patterns.
The Tailor and The Mice
Nov 15, 1997
A well-meaning tailor makes Pinky and Brain's lives miserable.
Bah, Wilderness
Nov 15, 1997
At a sleep away camp for world leaders' children, Brain tries to trick the children into placing listening devices in their parents' offices.
Pinky At The Bat
Nov 22, 1997
To release Brain's leather repellant, the mice become baseball players.
Schpiel-Borg 2000
Nov 22, 1997
Brain's latest plan for world domination is the Schpiel-Borg 2000, which hosts a retrospective of past episodes.
Broadway Malady
Jan 03, 1998
Pinky and Brain stage their own seperate musicals, which have varying degrees of success.
The Megalomaniacal Adventures of Brainie The Poo
Feb 07, 1998
Spoofing Winnie the Pooh, Brainie and Pinklet try to steal honey from a bee hive.
The Melancholy Brain
Feb 07, 1998
Brain tries to create chaos in Hamlet's family and take over.
Inherit The Wheeze
Feb 14, 1998
Brain tries to become a national hero by taking down a tobacco company.
Brain's Night Off
Feb 21, 1998
Taking the night off from trying to take over the world, Pinky and Brain try other things.
Beach Blanket Brain
Feb 21, 1998
Brain tries to get surfers to put on his suntan lotion, Brain de Soleil, which creates a hypnotic effect.
The Family That Poits Together, Narfs Together
Feb 21, 1998
Brain enters Pinky's family in a contest to win $25,000.
Pinky's Turn
Feb 28, 1998
Pinky has his own plan for world domination and Brain goes along with it.
Your Friend: Global Domination
Feb 28, 1998
Brain explains why he should be leader in a mock educational film.
You'll Never Eat Food Pellets In This Town Again
Apr 25, 1998
As network executives keep repeatedly changing their show, Pinky and Brain decide to quit.
Dangerous Brains
May 02, 1998
As he prepares his plan for world domination, Brain goes to work teaching rebellious students.
Whatever Happened To Baby Brain
May 09, 1998
Pinky and Brain masquerade as a mother and child star respectively to get money needed for the next plan.
Just Say Narf
May 09, 1998
Pinky sings a song about saying "narf".
The Pinky P.O.V.
May 16, 1998
It's another usual night where Brain plans to take over the world, only it's seen from Pinky's point of view.
The Really Great Dictator
May 16, 1998
The mice sing about world domination.
Brain Food
May 16, 1998
Brain opens a restaurant and feeds the customers a drug to make them smarter.
Season 4
No overview available for this season.
Brainwashed Pt. 1: Brain, Brain, Go Away
Sep 14, 1998
Pinky and Brain are kidnapped in Washington, DC by an unknown force. Brain loses his memory and the mice are then imprisoned in a town where everyone is forced to perform the Schëerskåhøvên, which is dumbing down the entire country.
Brainwashed Pt. 2: I Am Not a Hat
Sep 15, 1998
Brain regains his memory and the mice escape. They believe Snowball is responsible for the Schmëerskåhøvên, but him imprisoned in a mental institution.
Brainwashed Pt. 3: Wash Harder
Sep 16, 1998
The mice and Snowball search for the one who spliced their DNA, Dr. Mordough, thinking he's responsible for all this. But it turns out to be his cat, Precious, and time is running out.
To Russia With Lab Mice
Sep 21, 1998
Pinky and Brain's plan to alter caviar with a mutating capsule is complicated by a Russian lab mouse.
Hickory Dickory Bonk
Sep 21, 1998
Brain plots to make every clock on Earth chime repeatedly.
The Pinky And The Brain Reunion Special
Sep 21, 1998
A special of highlights of their career is on the air, but it's really all a ruse so Pinky and Brain can hypnotize the viewers.
A Legendary Tail
Sep 28, 1998
Inspired by legends of the past, Brain tries to create a legend about himself to gain world acclaim.
Project B.R.A.I.N.
Sep 28, 1998
How Acme Labs became home to Pinky and Brain.
Star Warners
Nov 04, 1998
In the series finale of Pinky and the Brain, the Brain, and the characters from Animaniacs develop a Star Wars spoof.